Effects of Aqueous Stem Bark Extract of Cissus Populnea on Serum Lipid Profile in Normal and Diabetic Induced Rats

The study form four weeks experimental protocol involving intragastric administration of 100mg/Kg body weight of aqueous stem bark extract of Cissus populnea in normal and alloxan induced diabetic albino rats. In the diabetes induced group there is a significant increase (P<0.05) in the serum level of cholesterol (2.80+ 0.46mmol/L 1.83+ from 0.08mmol/L). The result also revealed a significant increase in the serum level of HDL cholesterol (1.51+0.08 mmol/L from 1.08+ 0.05mmol/L). and of triglyceride (1.52+ 0.10mmol/L from 0.78+ 0.01mmol/L). However, no significant differences was observed in the serum level LDL cholesterol (1.30+ 0.01mmol/L and 1.30+ 0.12mmol/L). In the diabetic group administered with the extract there was a decrease in the level of cholesterol (1.83+ 0.08mmol/L to 1.06+0.15mmol/L). All other three lipid parameters increased signicantly (P><0.05)