Effects of the Ethanolic Extract of aerials of Leptadenia pyrotechnica (Forskk) Decne on the Liver function of Wister strain Albino Rats

The study was carried out to evaluate the subacute toxicity of the ethanolic extract of Leptadenia pyrotechnica (Forssk) Decne on the liver of wister strain albino rats. 20 rats were used and were divided into four groups of five rats each. First group received 50mg/kg body weight of the rats, second group received 100mg/kg body weight of the rats, third group received 150mg/kg body weight of the rats and the last group served as the control. The extract was administered for 21 days after which the serum of all rats was assayed for ALT, AST, ALP, Total protein and Albumin. The results of the liver function tests showed that the extract is mildly toxic to the liver of the rats.