PARASITE DENSITIES INFLUENCE ON THE WHITE BLOOD CELLS DISRIBUTION IN PLASMODIUM FALCIPARUM TREATED CHILDREN

This study was conducted on a sample size of 313 children enrolled, all suffered from uncomplicated Plasmodium falciparum malaria and treated with either Artesunate + Sulphadoxine - Pyrimethamine (AT+SP) and Amodiaquine + Sulphadoxine - Pyrimethamine (AQ+SP), the result assessed the influence of parasite densities on WBC distribution in children (6-59 months) treated over 28 days. The protocol on therapeutic efficacies of anti - malarial drugs was adopted. This shows a reduction in WBC with parasite depletion, the influence of parasitaemia on WBC was 92.92% for AT + SP compared to 87.66% for AQ + SP. The result further shows that for each μl of blood parasite clearance, there was a recovery in WBC by 0.5299 x109∕μl for AT + SP compared to 0.4597 x109∕μl for AQ + SP patients.