GC-MS analysis for Structural Identification and Bioactive Compounds in Methanolic Leaf Extract of Mallotus oppositifolius

Authors

  • Igwe K. K.1, Madubuike A.J.1, Otuokere I.E.2 Amaku F.J.3 Chika Ikenga 4.’ 1Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria. 2Departmemt of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria. 3 Physical Chemistry Research Lab, University of KwaZulu, Natal,Durban,South Africa. 4Recare Natural Products, Lagos, Nigeria, Nigeria
May 10, 2016

Downloads

The aim of the present study is to investigate the bioactive compounds from the leaf extract of Mallotus oppositifolius using GCMS analysis. The chromatogram showed nine peaks indicating the presence of nine compounds in the extract. The major phytocompounds in the leaf were Glutaconic anhydride with the highest concentration in the extract, 40.19 peak area %, RT 22.686 and molecular formula C5H4O3;  2-Mercaptophenol with  18.23 peak area %, RT 22.068 and molecular formula C6HOS. Iso-Valreic and Valeric acids with 12.39,2.53 peak area %, RT 3.676,7.037 and the same molecular formula C5H10 Owhich had been proposed to have anticonvulsant effect in valerian and act as neurotransmitter. Oleamide with the least concentration of 2.15 peak area %, RT 27.959 and molecular formula C18H35NO which could induce sleep in animals, being studied as a potential medical remedy for mood and sleep disorder and cannabinoid–regulated disorder. The phytochemicals in Mallotus oppositifolius could be of therapeutic importance.