Studies of the medicinal plant Pausinystalia yohimbe ethanol leaf extract phytocomponents by GCMS analysis

Authors

  • Igwe K. K.1, Madubuike A.J.1 , Chika Ikenga 2 , Otuokere I. E.3, Amaku F.J.4 1Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria. 2Recare Natural Products, Lagos, Nigeria 3Departmemt of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria. 4Physical Chemistry Research Lab, University of KwaZulu, Natal,Durban,South Africa., Nigeria
May 6, 2016

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An in vitro phytochemical study of ethanolic leaf extract of Pausinystalia yohimbe was done using Gas Chromatography-Mass Spectrometry to identify the presence or absence of erectile compounds. The chromatogram of the leaf of Pausinystalia yohimbe showed eight peaks indicating the presence of eight phytocompounds. The most abundant compound was Linoleic acid with a [Retention Time: 22.689; Peak Area: 52.99% ; Molecular Formula: C18H32O2] followed by n-Hexadecanoic acid with [Retention Time:19.91; Peak Area: 15.87% ; Molecular Formula: C16H32O2] followed by 2-Methylene-11-hexadecanoic acid with [Retention Time: 21.774; Peak Area: 7.57% ; Molecular Formula of C17H28O2]. Other components identified were 2,4-Dimethy-1,3-dioxane, n-Hexadecanoic acid, methyl ester, 11-phenyundecanoic acid, Octadecanoic acid and 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one. The bioactivities of Pausinystalia yohimbe leaf extract were anti-carcinogenic, lipid metabolism regulation, antioxidation, anti-atherosclerotic and antifungal from the GCMS result. Therefore the leaf of Pausinystalia yohimbe may be having bioactivities different from the bark which is known to contain yohimbine for erectile disfunction.